What should I expect
    after LILETTA insertion?

After your healthcare provider inserts LILETTA, you must be aware of a few key factors. Aside from understanding the Important Risk Information, you may have the following questions:

Yes, you should check that LILETTA is in proper position by feeling the threads. It is a good habit to do this 1 time a month.

Your healthcare provider should teach you how to check that LILETTA is in place.

  • First, wash your hands with soap and water.
  • You can check by reaching up to the top of your vagina with clean fingers to feel the threads.
  • Do not pull on the threads.

If you feel more than just the threads or if you cannot feel the threads, LILETTA may not be in the right position and may not prevent pregnancy. Use non-hormonal back-up birth control (such as condoms and spermicide) and ask your healthcare provider to check that LILETTA is still in the right place.

Call your healthcare provider if you have any questions or concerns. Otherwise, you should return to your healthcare provider for a follow-up visit 4 to 6 weeks after LILETTA is placed to make sure that LILETTA is in the right position.

For the first 3 to 6 months, your period may become irregular and the number of bleeding days may increase. You may also have frequent spotting or light bleeding and cramping. Some women have heavy bleeding during this time.

After you have used LILETTA for a while, the number of bleeding and spotting days is likely to lessen. For some women, menstrual periods will stop altogether. When LILETTA is removed, your menstrual periods will likely return to their former pattern.

You and your partner should not feel LILETTA during intercourse. LILETTA is placed in the uterus, not in the vagina. In some cases, your partner may feel the threads. If this occurs, or if you or your partner experience pain during sex, talk with your healthcare provider.

Call your healthcare provider right away if you think you are pregnant. If possible, also do a urine pregnancy test. If you get pregnant while using LILETTA, you may have an ectopic pregnancy. This means that the pregnancy is not in the uterus. Unusual vaginal bleeding or abdominal pain especially with missed periods may be a sign of ectopic pregnancy.

Ectopic pregnancy is a medical emergency that often requires surgery. Ectopic pregnancy can cause internal bleeding, infertility, and even death.

There are also risks if you get pregnant while using LILETTA and the pregnancy is in the uterus. Severe infection, miscarriage, premature labor, premature delivery, and even death can occur with pregnancies that continue with an intrauterine system (IUS). Because of this, your healthcare provider may try to remove LILETTA, even though removing it may cause a miscarriage. If LILETTA cannot be removed, talk with your healthcare provider about the benefits and risks of continuing the pregnancy.

If you continue your pregnancy, see your healthcare provider regularly. Call your healthcare provider right away if you get flu-like symptoms, fever, chills, cramping, pain, bleeding, vaginal discharge, or fluid leaking from your vagina. These may be signs of infection.

It is not known if LILETTA can cause long-term effects on the fetus if it stays in place during a pregnancy.

Call your healthcare provider if you have any concerns about LILETTA. Be sure to call if you:

  • think you are pregnant
  • have pelvic pain or pain during sex
  • have unusual vaginal discharge or genital sores
  • have unexplained fever, flu-like symptoms or chills
  • might be exposed to sexually transmitted infections (STIs)
  • are concerned that LILETTA may have been expelled (came out)
  • cannot feel LILETTA's threads
  • develop very severe or migraine headaches
  • have yellowing of the skin or whites of the eyes. These may be signs of liver problems.
  • have had a stroke or heart attack
  • you or your partner becomes HIV positive
  • have severe vaginal bleeding, bleeding that lasts a long time, or you miss your period

Call your healthcare provider if you have any concerns about LILETTA after it is inserted.

What I Need To Know About Insertion:

Before During After

LILETTA® (levonorgestrel-releasing intrauterine system) 52 mg is a hormone-releasing system placed in your uterus to prevent pregnancy for as long as you want for up to 4 years.


LILETTA does not protect against HIV or STDs.

Available by prescription only.

Please also see full Prescribing Information.


  1. LILETTA (levonorgestrel-releasing intrauterine system) 52 mg [Prescribing Information]. Irvine, CA: Allergan and Medicines360; 2017.
  2. "Women's Health Care Physicians." Long-Acting Reversible Contraception (LARC): IUD and Implant. 1 July 2014. Web. 6 Oct. 2015. http://www.acog.org/Patients/FAQs/Long-Acting-Reversible-Contraception-LARC-IUD-and-Implant.